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S2100000

Sulfamethoxazole

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide, N1-(5-Methylisoxazol-3-yl)sulfanilamide

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About This Item

Formula empirica (notazione di Hill):
C10H11N3O3S
Numero CAS:
723-46-6
Peso molecolare:
253.28
Beilstein:
6732984
Numero MDL:
MFCD00010546
Codice UNSPSC:
41116107
ID PubChem:
329824505
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

sulfamethoxazole

Produttore/marchio commerciale

EDQM

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1

InChI

1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
JLKIGFTWXXRPMT-UHFFFAOYSA-N

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Sulfamethoxazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

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1631001

Sulfamethoxazole, United States Pharmacopeia (USP) Reference Standard

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Y0000412

Sulfamethoxazole impurity A, European Pharmacopoeia (EP) Reference Standard

Y0000413

Sulfamethoxazole impurity F, European Pharmacopoeia (EP) Reference Standard

1631533

Sulfamethoxazole Related Compound C, United States Pharmacopeia (USP) Reference Standard

1631511

Sulfamethoxazole Related Compound A, United States Pharmacopeia (USP) Reference Standard

1631566

Sulfamethoxazole Related Compound F, United States Pharmacopeia (USP) Reference Standard

1631522

Sulfamethoxazole Related Compound B, United States Pharmacopeia (USP) Reference Standard

BP314

Sulfamethoxazole, British Pharmacopoeia (BP) Reference Standard

PHR2577

Sulfamethoxazole Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2578

Sulfamethoxazole Impurity A

Pittogrammi

Health hazardEnvironment
GHS08,GHS09

Avvertenze

Warning

Indicazioni di pericolo

H361fd,H411

Classi di pericolo

Aquatic Chronic 2 - Repr. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

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Certificati d'analisi (COA)

Lot/Batch Number

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Raquel González et al.
PLoS medicine, 11(9), e1001735-e1001735 (2014-09-24)
Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for malaria prevention in HIV-negative pregnant women, but it is contraindicated in HIV-infected women taking daily cotrimoxazole prophylaxis (CTXp) because of potential added risk of adverse effects associated with
R E Levitz et al.
Annals of internal medicine, 100(6), 881-890 (1984-06-01)
Trimethoprim-sulfamethoxazole has excellent microbiologic activity against most pathogens that produce meningitis; both components of this drug have high penetration into tissues, including the cerebrospinal fluid. Clinical experience shows that trimethoprim-sulfamethoxazole may be beneficial in the treatment of gram-negative bacillary meningitis
Co-trimoxazole (trimethoprim-sulfamethoxazole): an updated review of its antibacterial activity and clinical efficacy.
G P Wormser et al.
Drugs, 24(6), 459-518 (1982-12-01)
Jih-Tay Hsu et al.
Journal of hazardous materials, 277, 34-43 (2014-03-19)
Antibiotics are commonly used in swine feed to treat and prevent disease, as well as to promote growth. Antibiotics released into the environment via wastewater could accelerate the emergence of antibiotic-resistant bacteria and resistance genes in the surrounding environment. In
D H Lawson et al.
Reviews of infectious diseases, 4(2), 429-433 (1982-03-01)
A comprehensive review is presented of the world literature on adverse reactions to trimethoprim-sulfamethoxazole (TMP-SMZ) since its first use in 1968, when concern was expressed about possible hematologic toxicity. Serious toxicity is a rare event, but when it occurs severe
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