BP1094

Cyclophosphamide

British Pharmacopoeia (BP) Reference Standard

• Sinonimo/i: Cyclophosphamide monohydrate, 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, Cytoxan
• Formula empirica (notazione di Hill): C₇H₁₅Cl₂N₂O₂P · H₂O
• Numero CAS: 6055-19-2
• Peso molecolare: 279.10
• Beilstein: 4678992
• Numero MDL: MFCD00149395
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: cyclophosphamide
• Forma fisica: crystalline
• Durata: limited shelf life, expiry date on the label
• Produttore/marchio commerciale: BP
• Punto di fusione: 49-51 °C (lit.)
• applicazioni: pharmaceutical; pharmaceutical small molecule
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: [H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
• InChI: 1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2; PWOQRKCAHTVFLB-UHFFFAOYSA-N

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Cyclophosphamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Cyclophosphamide Oral Solution

Azioni biochim/fisiol

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.

Confezionamento

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H301,H340,H350,H360FD
• Consigli di prudenza: P202 - P264 - P270 - P280 - P301 + P310 - P405
• Classi di pericolo: Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 235.4 °F - closed cup
• Punto d’infiammabilità (°C): 113 °C - closed cup