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74309

Supelco

Padimate O

analytical standard

Sinonimo/i:

2-Ethylhexyl 4-(dimethylamino)benzoate

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About This Item

Formula condensata:
(CH3)2NC6H4CO2CH2CH(C2H5)(CH2)3CH3
Numero CAS:
21245-02-3
Peso molecolare:
277.40
Numero CE:
244-289-3
Numero MDL:
MFCD00017526
Codice UNSPSC:
41116107
ID PubChem:
329765613
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

100

Saggio

≥98.0% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Indice di rifrazione

n20/D 1.541±0.001
n20/D 1.542 (lit.)

P. eboll.

325 °C (lit.)

Densità

0.995 g/mL at 25 °C (lit.)

applicazioni

cleaning products
cosmetics
environmental
food and beverages
personal care

Formato

neat

Stringa SMILE

CCCCC(CC)COC(=O)c1ccc(cc1)N(C)C

InChI

1S/C17H27NO2/c1-5-7-8-14(6-2)13-20-17(19)15-9-11-16(12-10-15)18(3)4/h9-12,14H,5-8,13H2,1-4H3
WYWZRNAHINYAEF-UHFFFAOYSA-N

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Descrizione generale

Padimate O is a tertiary amine derivative of p-aminobenzoic acid (PABA), which is commonly used as a sunscreen agent in cosmetics and other sunscreen formulations due to its ability to absorb ultraviolet radiations.

Applicazioni

Padimate O may be used as a reference standard in the determination of padimate O in cosmetics using high performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H360FD

Classi di pericolo

Repr. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

374.0 °F - closed cup

Punto d’infiammabilità (°C)

190 °C - closed cup

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
BCCD8748
BCBZ8379
BCBV2153
BCBQ9627V
BCBM6428V

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1-Hydroxycyclohexyl phenyl ketone 99%

Sigma-Aldrich

405612

1-Hydroxycyclohexyl phenyl ketone

Adsorbente polimerico poroso Tenax® matrix Tenax TA (refined), 60-80 mesh, bottle of 100 g

Supelco

12168-U

Adsorbente polimerico poroso Tenax®

Ethyl 4-(dimethylamino)benzoate ≥99%

Sigma-Aldrich

E24905

Ethyl 4-(dimethylamino)benzoate

Homosalate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1085

Homosalate

Octisalate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1081

Octisalate

In vitro skin absorption and metabolism of Padimate-O and a nitrosamine formed in Padimate-O-containing cosmetic products.
Kenney EG, et al.
Journal of Society of Cosmetic Chemists of Japan, 46(2), 117-117 (1995)
Assay of mixtures of padimate-O and oxybenzone in sunscreen formulations by high-performance liquid chromatography.
Tan ISH, et al.
Journal of Chromatography A, 291, 275-282 (1984)
Ana Gil-Vergara et al.
Analytical and bioanalytical chemistry, 389(2), 605-617 (2007-07-25)
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) and gas chromatography-mass spectrometry (GC-MS) have been compared for the analysis of 2-isopropyl thioxanthone (ITX) and 2-ethylhexyl-4-dimethylaminobenzoate (EHDAB). Pressurized liquid extraction (PLE) was applied for the extraction of ITX and EHDAB from milk and milk-based
S H Dromgoole et al.
Journal of the American Academy of Dermatology, 22(6 Pt 1), 1068-1078 (1990-06-01)
Reports in the literature of sensitization associated with many commonly used sunscreening agents including p-aminobenzoic acid (PABA), PABA derivatives, anthranilates, salicylates, cinnamates, benzophenones, and dibenzoylmethane derivatives are reviewed. Several of these case reports involved subjects with various photodermatoses, implicating enhanced
R Bestak et al.
The Journal of investigative dermatology, 105(3), 345-351 (1995-09-01)
This study compares the ability of two ultraviolet (UV) B-absorbing sunscreens, 2-ethylhexyl p-methoxycinnamate (2-EHMC) and 2-ethylhexyl p-aminobenzoate (Padimate O), and two physical sunscreens, microfine titanium dioxide (MTD) and zinc oxide, to protect the skin immune system from chronic (4 weeks)
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