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Documenti

18189

Supelco

2,4-Dinitrophenylhydrazine hydrochloric acid solution

~0.005 M in ethanol, for TLC derivatization

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About This Item

Formula empirica (notazione di Hill):
C6H6N4O4
Numero CAS:
119-26-6
Peso molecolare:
198.14
Beilstein:
615586
Numero MDL:
MFCD00007578
Codice UNSPSC:
41116105
ID PubChem:
329751648
NACRES:
NA.22

Grado

for TLC derivatization

Livello qualitativo

100

Concentrazione

~0.005 M in ethanol

tecniche

thin layer chromatography (TLC): suitable

Indice di rifrazione

n20/D 1.374

Densità

0.843 g/mL at 20 °C

Compatibilità

in accordance for application

Temperatura di conservazione

2-8°C

Stringa SMILE

NNc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O

InChI

1S/C6H6N4O4/c7-8-5-2-1-4(9(11)12)3-6(5)10(13)14/h1-3,8H,7H2
HORQAOAYAYGIBM-UHFFFAOYSA-N

Descrizione generale

2,4-Dinitrophenylhydrazine hydrochloric acid solution is a derivatization reagent.

Applicazioni

2,4-dinitrophenylhydrazine HCl solution was used in detecting Artemisinin derivatives usingf TLC silica gel sheets. It may be used in determination of carbonyl groups. It may also be used in a procedure for coating in situ silica gel with prepacked cartridges.

Pittogrammi

FlameCorrosion
GHS02,GHS05

Avvertenze

Danger

Indicazioni di pericolo

H225,H290,H319

Classi di pericolo

Eye Irrit. 2 - Flam. Liq. 2 - Met. Corr. 1

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

57.2 °F

Punto d’infiammabilità (°C)

14.0 °C

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number
BCBV4278
BCBN7623V
BCBL5811V
BCBJ0039V
BCBG4540V

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R Fields et al.
The Biochemical journal, 121(4), 587-589 (1971-02-01)
A method is described for determining carbonyl groups that is especially suitable for use with proteins and peptides. It involves the determination of the extinction at 370nm of a sample solution after adding 2,4-dinitrophenylhydrazine. The reaction of 2,4-dinitrophenylhydrazine with pyruvoylglycine
Jean-Robert Ioset et al.
PloS one, 4(9), e7270-e7270 (2009-10-01)
Malaria continues to be one of the major public health problems in Africa, Asia and Latin America. Artemisinin derivatives (ARTs; artesunate, artemether, and dihydroartemisinin) derived from the herb, Artemisia annua, are the most effective antimalarial drugs available providing rapid cures.
S B Tejada
International journal of environmental analytical chemistry, 26(2), 167-185 (1986-01-01)
A procedure for coating in situ silica gel in prepacked cartridges with 2,4-dinitrophenylhydrazine (DNPH) acidified with hydrochloric acid is described. The coated cartridge was compared with a validated DNPH impinger method for sampling organic carbonyl compounds (aldehydes and ketones) in
Ravi Ch Bollineni et al.
Journal of proteomics, 74(11), 2351-2359 (2011-06-15)
Reactive oxygen species (ROS) can oxidize proteins at almost any amino acid residue. Whereas some modifications are reversible within the cells, the higher oxidation states are especially irreversible. These irreversible post translational modifications are widely used as biomarkers of oxidative
María Linares et al.
Journal of proteome research, 10(4), 1719-1727 (2011-01-18)
Oxidative stress plays a critical role in the pathogenesis of a number of diseases. The carbonyl end products of protein oxidation are among the most commonly measured markers of oxidation in biological samples. Protein carbonyl functional groups may be derivatized
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