MAB4356

Anti-DPPA-2 Antibody, clone 6C1.2

clone 6C1.2, from mouse

• Sinonimo/i: Pluripotent embryonic stem cell-related gene 1 protein, developmental pluripotency associated 2
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: primary antibodies
• Clone: 6C1.2, monoclonal
• Reattività contro le specie: mouse
• tecniche: western blot: suitable
• input: sample type: mouse embryonic stem cell(s)
• Isotipo: IgG2aκ
• N° accesso UniProt: Q7Z7J5; Q9CWH0
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: mouse ... Dppa2(73703)

Descrizione

Descrizione generale

DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells.

Specificità

Reactivity with other species has not been tested.

This monoclonal antibody recognizes the mouse DPPA-2 protein.

Immunogeno

Full length recombinant mouse DPPA-2 protein.

Applicazioni

Research Category
Stem Cell Research

Research Sub Category
Pluripotent & Early Differentiation

This Anti-DPPA-2 Antibody, clone 6C1.2 is validated for use in WB for the detection of DPPA-2.

Qualità

(Based upon representative data from a previous lot).
Western Blotting: Recommended working concentration is 2 µg/mL.

Descrizione del bersaglio

~34 kDa

Stato fisico

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2a_κ in buffer containing 0.1 M Tris-Glycine (pH 7.4) and
150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable