204910

Complement C9, Human

Complement C9, Human, CAS 80295-59-6, is a native, single-chain glycoprotein present in normal human serum at 60 µg/ml.

• Sinonimo/i: Complement C9, Human
• Numero CAS: 80295-59-6
• Numero MDL: MFCD00130849
• Codice UNSPSC: 12352202
• NACRES: NA.25

Proprietà

• Livello qualitativo: 200
• Saggio: ≥95% (SDS-PAGE)
• Forma fisica: liquid
• Attività specifica: ≥150,000 C9H50 units/mg
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; avoid repeated freeze/thaw cycles
• Impurezze: IgG, IgA, IgM, albumin, C3, C4, C5, C6, C7, or C8, trace
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −70°C

Descrizione

Descrizione generale

Native, human C9 complement component. Single-chain glycoprotein present in normal human serum at 60 µg/ml. On activation of complement via either the classical or alternative pathway, formation of the C5b fragment initiates assembly of C5b-9 complement membrane attack complex (MAC) on target surfaces. Full lytic activity of MAC occurs only after binding of three to six C9 molecules to each C5b-8 complex.

Native, human C9 complement component. Single-chain glycoprotein present in normal human serum at 60 µg/ml. On activation of complement via either the classical or alternative pathway, formation of the C5b fragment initiates assembly of the C5b-9 complement membrane attack complex (MAC) on target surfaces. Full lytic activity of MAC occurs only after binding of three to six C9 molecules to each C5b-8 complex.

Confezionamento

Please refer to vial label for lot-specific concentration.

Attenzione

Toxicity: Standard Handling (A)

Stato fisico

In PBS, pH 7.2, filtered through a 0.22 µm pore size filter.

Nota sulla preparazione

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Ricostituzione

Following initial thaw, aliquot and freeze (-70°C).

Altre note

Stanley, K.K., et al. 1985. EMBO J. 4, 375.
Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable