07-748-AF647

Anti-monomethyl Histone H4 (Lys20) Antibody, Alexa Fluor^™ 647 Conjugate

0.5 mg/mL, from rabbit

• Sinonimo/i: Histone H4
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: ALEXA FLUOR^™ 647
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Reattività contro le specie: human
• Concentrazione: 0.5 mg/mL
• tecniche: immunocytochemistry: suitable
• N° accesso NCBI: NM_001034077.4
• N° accesso UniProt: P62805; Q6DRA9
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: monomethylation (Lys20)
• Informazioni sul gene: human ... HIST2H4B(554313)

Descrizione

Descrizione generale

Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The histones have an amino terminal tail, a globular domain, and a carboxy-terminal tail. The four core histones, H2A, H2B, H3 and H4 assemble into the octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped in a sequence-independent manner around the octamer, forming the basic subunit of chromatin, the nucleosome. Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail, H4 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. This product is a conjugated version of Cat. No. 07-748.

Immunogeno

Linear peptide corresponding to Histone H4 monomethylated at Lys20.

Applicazioni

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

This Anti-monomethyl Histone H4 (Lys20) Antibody, Alexa Fluor^™ 647 Conjugate is validated for use in ICC for the detection of monomethyl Histone H4 (Lys20).

Qualità

Evaluated by Immunocytochemistry in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected monomethyl Histone H4 (Lys20) in HeLa cells.

Alexa Fluor^™ is a registered trademark of Life Technologies.

Descrizione del bersaglio

~10 kDa observed (Refer to Cat. No. 07-748)

Stato fisico

Protein A purified

Purified rabbit conjugated antibody in buffer containing PBS and 15 mg/ml BSA with 0.1% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Note legali

ALEXA FLUOR is a trademark of Life Technologies

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2