492876
L-Alanine-12C3
99.9 atom % 12C
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About This Item
Formula condensata:
12CH312CH(NH2)12CO2H
Numero CAS:
Peso molecolare:
89.06
Beilstein:
1720248
Numero CE:
Numero MDL:
Codice UNSPSC:
12352209
ID PubChem:
Descrizione
13C-depleted
Purezza isotopica
99.9 atom % 12C
Attività ottica
[α]25/D +14.5°, c = 2 in 1 M HCl
Disponibilità
available only in Japan
Punto di fusione
314.5 °C (dec.) (lit.)
Spostamento di massa
depleted
Stringa SMILE
[12CH3][12C@H](N)[12C](O)=O
InChI
1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1/i1+0,2+0,3+0
QNAYBMKLOCPYGJ-BWIFZRRMSA-N
Categorie correlate
Azioni biochim/fisiol
L-Alanine is a nonessential amino acid, which is highly concentrated in muscle. It is a key player in the Glucose-Alanine cycle, which enables the removal of pyruvate and glutamate from muscle to the liver. Once in the liver, glucose is regenerated from pyruvate and returned to the muscle while glutamate ultimately participates in the urea cycle to form urea. The Glucose-Alanine cycle aides to conserve ATP in muscle for muscle contraction, while the energy burden of gluconeogenesis is imposed upon the liver. Alanine inhibits pyruvate kinase to regulate gluconeogenesis and glycolysis in order to maintain glucose homeostasis during starvation. Alanine prevents hepatic autophagy. Alanine formation is a result of transamination of glutamate and pyruvate.
Confezionamento
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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Alanine and glutamine synthesis and release from skeletal muscle. II. The precursor role of amino acids in alanine and glutamine synthesis.
Garber A J, et al.
The Journal of Biological Chemistry, 251(3), 836-843 (1976)
Muscle alanine synthesis and hepatic gluconeogenesis
Snell K
Biochemical Society Transactions, 8(2), 205-213 (1980)
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