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Merck

ZYX

zyxin

Sinonimi:
ESP-2, HED-2
Specie:
ID UniProtKB:
ID gene:
  • Human(7791) Summary: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(22793) zyxin
  • Rat(114636) zyxin
  • fruit fly(317824) Zyxin
  • dog(482736) zyxin
  • domestic cat(101099953) zyxin
  • Zebrafish(564246) zyxin
  • chicken(418300) zyxin
  • cow(768226) zyxin
  • sheep(101123626) zyxin
  • domestic guinea pig(100727523) zyxin
  • naked mole-rat(101710025) zyxin

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-ZYX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
Anti-Zyxin, serum, from rabbit,
Reattività con
human, monkey, mouse
Applicazione
immunocytochemistry
western blot
Anti-ZYX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Monoclonal Anti-ZYX antibody produced in mouse, clone 2C10-4A7, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence

immunoprecipitation (IP)

western blot
Anti-ZYX antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
canine, human
Applicazione
ELISA
western blot

Proteins

N° Catalogo
Descrizione
Specie
Monoclonal Anti-ZYX antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2502, purified immunoglobulin, buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Zyx,
Specie
mouse