VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor
Sinonimi:
NR1I1
Specie:
Human VDR (7421), Mouse Vdr (22337), Rat Vdr (24873), chicken VDR (395988), dog VDR (486588), Horse VDR (100034072), domestic cat VDR (100316614), cow VDR (533656), sheep VDR (101107273), sheep VDR (100294603) ...Più
ID UniProtKB:
ID gene:
- Human(7421) Summary: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011]
- Mouse(22337) vitamin D receptor
- Rat(24873) vitamin D (1,25- dihydroxyvitamin D3) receptor
- chicken(395988) vitamin D (1,25- dihydroxyvitamin D3) receptor
- dog(486588) vitamin D (1,25- dihydroxyvitamin D3) receptor
- Horse(100034072) vitamin D (1,25- dihydroxyvitamin D3) receptor
- domestic cat(100316614) vitamin D (1,25- dihydroxyvitamin D3) receptor
- cow(533656) vitamin D (1,25- dihydroxyvitamin D3) receptor
- sheep(101107273) vitamin D (1,25- dihydroxyvitamin D3) receptor
- sheep(100294603) vitamin D (1,25- dihydroxyvitamin D3) receptor
- naked mole-rat(101710294) vitamin D (1,25- dihydroxyvitamin D3) receptor
- domestic guinea pig(100734655) vitamin D (1,25- dihydroxyvitamin D3) receptor
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Small Molecule - Agonist
N° Catalogo
Descrizione
Specie
Vitamin D3 solution, 1 mg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Small Molecule - Antagonist
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Vitamin D Receptor antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-VDR antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
immunofluorescence
western blot
western blot
Anti-Vitamin D3 Receptor Antibody, clone 1M19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
bovine, canine, feline, human, monkey, mouse, porcine, rat
Applicazione
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-VDR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Monoclonal Anti-VDR antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunohistochemistry
immunohistochemistry
esiRNA
N° Catalogo
Descrizione
Specie