UMOD
uromodulin
Sinonimi:
ADMCKD2, FJHN, HNFJ, HNFJ1, MCKD2, THGP, THP
Specie:
Human UMOD (7369), Mouse Umod (22242), Rat Umod (25128), domestic cat UMOD (101084248), dog UMOD (403510), cow UMOD (281567), sheep UMOD (101119604), naked mole-rat Umod (101709895), domestic guinea pig Umod (100730507)
ID UniProtKB:
ID gene:
- Human(7369) Summary: The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- Mouse(22242) uromodulin
- Rat(25128) uromodulin
- domestic cat(101084248) uromodulin
- dog(403510) uromodulin
- cow(281567) uromodulin
- sheep(101119604) uromodulin
- naked mole-rat(101709895) uromodulin
- domestic guinea pig(100730507) uromodulin
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Descrizione
Specie
Antibodies
Product Number
Descrizione
Reattività con
Applicazione
Anti-UMOD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-UMOD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-UMOD antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-UMOD antibody produced in mouse, clone 3F10, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Proteins
Product Number
Descrizione
Specie
esiRNA
Product Number
Descrizione
Specie