SNCA
synuclein, alpha (non A4 component of amyloid precursor)
Sinonimi:
NACP, PARK1, PARK4, PD1
Specie:
Human SNCA (6622), Mouse Snca (20617), Rat Snca (29219), chicken SNCA (395393), Horse SNCA (100053270), domestic cat SNCA (101091694), dog SNCA (478478), cow SNCA (282857), sheep SNCA (100294604), domestic guinea pig Snca (100725375)
ID UniProtKB:
ID gene:
- Human(6622) Summary: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
- Mouse(20617) synuclein, alpha
- Rat(29219) synuclein, alpha (non A4 component of amyloid precursor)
- chicken(395393) synuclein, alpha (non A4 component of amyloid precursor)
- Horse(100053270) synuclein, alpha (non A4 component of amyloid precursor)
- domestic cat(101091694) synuclein, alpha (non A4 component of amyloid precursor)
- dog(478478) synuclein, alpha (non A4 component of amyloid precursor)
- cow(282857) synuclein, alpha (non A4 component of amyloid precursor)
- sheep(100294604) synuclein, alpha (non A4 component of amyloid precursor)
- domestic guinea pig(100725375) synuclein, alpha (non A4 component of amyloid precursor)
- naked mole-rat(101700039) synuclein, alpha (non A4 component of amyloid precursor)
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-phospho-α-synuclein (Ser129) Antibody, clone PS129, ,
Reattività con
bovine, human, mouse, porcine, rat
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anticorpo anti-alfa-sinucleina aggregata, clone 5G4, clone 5G4, from mouse, purified by affinity chromatography,
Reattività con
human
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anticorpo anti-fosfo-α-sinucleina (Ser129), clone 81A, clone 81A, from mouse,
Reattività con
human, mouse
Applicazione
electron microscopy
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-α-Synuclein antibody, Mouse monoclonal, clone Syn211, purified from hybridoma cell culture,
Reattività con
human, zebra finch
Applicazione
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anticorpo anti-α-sinucleina, clone Syn211, ascites fluid, clone Syn211, Upstate®,
Reattività con
human
Applicazione
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Proteins
N° Catalogo
Descrizione
Specie
α-Synuclein human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
Specie
human
α-Synuclein A53T human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
Specie
human
α-Synuclein E46K, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
Specie
human