Passa al contenuto
Merck

NANS

N-acetylneuraminic acid synthase

Sinonimi:
SAS
Specie:
ID UniProtKB:
ID gene:
  • Human(54187) Summary: This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq, Jul 2008]
  • Mouse(94181) N-acetylneuraminic acid synthase (sialic acid synthase)
  • Rat(298071) N-acetylneuraminic acid synthase
  • sheep(101104048) N-acetylneuraminic acid synthase
  • domestic guinea pig(100716456) N-acetylneuraminic acid synthase
  • naked mole-rat(101721582) N-acetylneuraminic acid synthase
  • Domestic Rabbit(100356934) N-acetylneuraminic acid synthase
  • Zebrafish(322780) N-acetylneuraminic acid synthase
  • chicken(427283) N-acetylneuraminic acid synthase
  • domestic cat(101092303) N-acetylneuraminic acid synthase
  • cow(540602) N-acetylneuraminic acid synthase
  • Horse(100064126) N-acetylneuraminic acid synthase
  • dog(481624) N-acetylneuraminic acid synthase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Descrizione
Reattività con
Applicazione
Anti-NANS antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anti-NANS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-NANS antibody produced in mouse, clone 3G6, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot

esiRNA

Product Number
Descrizione
Specie
MISSION® esiRNA, targeting human NANS,
Specie
human
MISSION® esiRNA, targeting mouse Nans,
Specie
mouse