MYLK
myosin light chain kinase
Sinonimi:
AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK
Specie:
Human MYLK (4638), Mouse Mylk (107589), Rat Mylk (288057), chicken MYLK (396445), dog MYLK (488012), Horse MYLK (100070482), cow MYLK (338037), naked mole-rat Mylk (101704236), Domestic Rabbit MYLK (100009143), domestic guinea pig Mylk (100714177)
ID UniProtKB:
ID gene:
- Human(4638) Summary: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
- Mouse(107589) myosin, light polypeptide kinase
- Rat(288057) myosin light chain kinase
- chicken(396445) myosin light chain kinase
- dog(488012) myosin light chain kinase
- Horse(100070482) myosin light chain kinase
- cow(338037) myosin light chain kinase
- naked mole-rat(101704236) myosin light chain kinase
- Domestic Rabbit(100009143) myosin light chain kinase
- domestic guinea pig(100714177) myosin light chain kinase
- sheep(443334) myosin light chain kinase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Descrizione
Reattività con
Applicazione
Monoclonal Anti-Myosin Light Chain Kinase antibody produced in mouse, clone K36, ascites fluid,
Reattività con
avian, mammals
Applicazione
immunoprecipitation (IP)
microarray
western blot
microarray
western blot
Anti-MYLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
western blot
Anti-MYLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-MYLK antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
ELISA
western blot
western blot
Monoclonal Anti-MYLK antibody produced in mouse, clone 1D1, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
western blot
Small Molecule - Inhibitor
Product Number
Descrizione
Specie
Proteins
Product Number
Descrizione
Specie
MLCK Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, human MLCK, amino acids 1425-1771, for use in Kinase Assays.,
Specie
human
MLCK (1425-1776), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human