Passa al contenuto
Merck

MMP1

matrix metallopeptidase 1 (interstitial collagenase)

Sinonimi:
CLG, CLGN
Specie:
ID UniProtKB:
ID gene:
  • Human(4312) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
  • Rat(300339) matrix metallopeptidase 1 (interstitial collagenase)
  • Rat(432357) matrix metalloproteinase 1
  • sheep(101120355) matrix metallopeptidase 1 (interstitial collagenase)
  • domestic guinea pig(100727966) matrix metallopeptidase 1 (interstitial collagenase)
  • naked mole-rat(101697620) matrix metallopeptidase 1 (interstitial collagenase)
  • Domestic Rabbit(100009110) matrix metallopeptidase 1 (interstitial collagenase)
  • fruit fly(37949) Matrix metalloproteinase 1
  • dog(489428) matrix metallopeptidase 1 (interstitial collagenase)
  • cow(281308) matrix metallopeptidase 1 (interstitial collagenase)
  • Horse(100033896) matrix metallopeptidase 1 (interstitial collagenase)
  • chicken(418982) matrix metallopeptidase 1 (interstitial collagenase)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

N° Catalogo
Descrizione
Specie
Human MMP-1 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Specie
human
Human MMP-1 ELISA Kit, for cell and tissue lysates,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Matrix Metalloproteinase-1 antibody produced in goat, affinity isolated antibody, lyophilized powder,
Reattività con
human
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Anti-MMP-1 (Ab-1) Mouse mAb (41-1E5), liquid, clone 41-1E5, Calbiochem®,
Reattività con
human
Applicazione
Anticorpo Anti-MMP-1, a.a. 332-350 hMMP1, clone 41-1E5, clone 41-1E5, Chemicon®, from mouse,
Reattività con
human, rabbit
Applicazione
ELISA
immunohistochemistry

western blot
Anti-MMP1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anti-MMP1 antibody produced in rabbit, ,
Reattività con
human
Applicazione
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Doxycycline monohydrate, ,
Specie
human
Doxycycline Monohydrate, United States Pharmacopeia (USP) Reference Standard,
Specie
human
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Specie
human, rat, mouse
Marimastat, ≥98% (HPLC),
Specie
human, rat, mouse
CP-101537, ≥98% (HPLC),
Specie
human, rat, mouse

Proteins

N° Catalogo
Descrizione
Specie
MMP-1 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Specie
human
Matrix Metalloproteinase-1, recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous solution,
Specie
human
Collagen Type I−FITC Conjugate from bovine skin, ~1 mg/mL, solution,
Specie
cow, rat, human, mouse

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human MMP1,
Specie
human