LEPR
leptin receptor
Sinonimi:
CD295, LEP-R, LEPRD, OB-R, OBR
Specie:
Human LEPR (3953), Mouse Lepr (16847), Rat Lepr (24536), sheep LEPR (443264), domestic guinea pig Lepr (100725434), naked mole-rat Lepr (101705981), Zebrafish lepr (567241), dog LEPR (450207), domestic cat LEPR (101085646), cow LEPR (497205) ...Più
ID UniProtKB:
ID gene:
- Human(3953) Summary: The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]
- Mouse(16847) leptin receptor
- Rat(24536) leptin receptor
- sheep(443264) leptin receptor
- domestic guinea pig(100725434) leptin receptor
- naked mole-rat(101705981) leptin receptor
- Zebrafish(567241) leptin receptor
- dog(450207) leptin receptor
- domestic cat(101085646) leptin receptor
- cow(497205) leptin receptor
- Horse(100033894) leptin receptor
- chicken(374223) leptin receptor
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
N° Catalogo
Descrizione
Specie
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-LEPR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-Leptin Receptor antibody produced in goat, affinity isolated antibody, lyophilized powder,
Reattività con
mouse
Applicazione
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Leptin Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot