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Merck

ERCC5

excision repair cross-complementing rodent repair deficiency, complementation group 5

Sinonimi:
COFS3, ERCM2, UVDR, XPG, XPGC
Specie:
ID UniProtKB:
ID gene:
  • Human(2073) Summary: This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011]
  • Mouse(22592) excision repair cross-complementing rodent repair deficiency, complementation group 5
  • Rat(301382) excision repair cross-complementing rodent repair deficiency, complementation group 5
  • domestic guinea pig(100734193) excision repair cross-complementing rodent repair deficiency, complementation group 5
  • naked mole-rat(101723410) excision repair cross-complementing rodent repair deficiency, complementation group 5
  • sheep(101114031) excision repair cross-complementing rodent repair deficiency, complementation group 5
  • Domestic Rabbit(100338146) excision repair cross-complementing rodent repair deficiency, complementation group 5
  • Zebrafish(541502) excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome))
  • cow(509602) excision repair cross-complementing rodent repair deficiency, complementation group 5
  • Horse(100063431) excision repair cross-complementing rodent repair deficiency, complementation group 5
  • domestic cat(101085685) excision repair cross-complementing rodent repair deficiency, complementation group 5
  • dog(485540) excision repair cross-complementing rodent repair deficiency, complementation group 5
  • chicken(428019) excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome))

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-ERCC5 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
western blot
Anti-ERCC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
Anti-ERCC5 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rabbit, rat
Applicazione
western blot
Anti-ERCC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-ERCC5 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Ercc5,
Specie
mouse
MISSION® esiRNA, targeting human ERCC5,
Specie
human