CTSB
cathepsin B
Sinonimi:
APPS, CPSB
Specie:
Human CTSB (1508), Mouse Ctsb (13030), Rat Ctsb (64529), chicken CTSB (396329), dog CTSB (486077), domestic cat CTSB (101084873), cow CTSB (281105), Horse CTSB (100060963), sheep CTSB (780470), naked mole-rat Ctsb (101709008)
ID UniProtKB:
ID gene:
- Human(1508) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(13030) cathepsin B
- Rat(64529) cathepsin B
- chicken(396329) cathepsin B
- dog(486077) cathepsin B
- domestic cat(101084873) cathepsin B
- cow(281105) cathepsin B
- Horse(100060963) cathepsin B
- sheep(780470) cathepsin B
- naked mole-rat(101709008) cathepsin B
- domestic guinea pig(100714169) cathepsin B
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Descrizione
Reattività con
Applicazione
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Cathepsin B (Ab-1) Mouse mAb (CA10), lyophilized, clone CA10, Calbiochem®,
Reattività con
bovine, human, porcine
Applicazione
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
immunohistochemistry
Monoclonal Anti- Cathepsin B, clone CB59-4B11, purified from hybridoma cell culture,
Reattività con
human, rat
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Cathepsin B, from rabbit, purified by affinity chromatography,
Reattività con
human, rat
Applicazione
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Descrizione
Specie
Cathepsin B from human liver, buffered aqueous solution, ≥1,500 units/mg protein (E1%/280),
Specie
human
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Specie
human
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Specie
human
esiRNA
Small Molecule - Substrate
Product Number
Descrizione
Specie