Passa al contenuto
Merck

CHUK

conserved helix-loop-helix ubiquitous kinase

Sinonimi:
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
Specie:
Human CHUK (1147), Mouse Chuk (12675), Rat Chuk (309361), Zebrafish chuk (393287), cow CHUK (281073), Horse CHUK (100070393), dog CHUK (477796), chicken CHUK (423669), domestic cat CHUK (101095617), sheep CHUK (101111143) ...Più
ID UniProtKB:
O15111, O14666, Q13132, Q5W0I4, Q92467
ID gene:
  • Human(1147) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • Mouse(12675) conserved helix-loop-helix ubiquitous kinase
  • Rat(309361) conserved helix-loop-helix ubiquitous kinase
  • Zebrafish(393287) conserved helix-loop-helix ubiquitous kinase
  • cow(281073) conserved helix-loop-helix ubiquitous kinase
  • Horse(100070393) conserved helix-loop-helix ubiquitous kinase
  • dog(477796) conserved helix-loop-helix ubiquitous kinase
  • chicken(423669) conserved helix-loop-helix ubiquitous kinase
  • domestic cat(101095617) conserved helix-loop-helix ubiquitous kinase
  • sheep(101111143) conserved helix-loop-helix ubiquitous kinase
  • domestic guinea pig(100726357) conserved helix-loop-helix ubiquitous kinase
  • naked mole-rat(101719306) conserved helix-loop-helix ubiquitous kinase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
SAB5700523
Anti-Phospho-IKKα/β-S176/180 antibody produced in rabbit, ,
Reattività con
human
Applicazione
western blot
SAB4300396
Anti-CHUK (Ab-23) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
ZRB1673
Anti-p-IKKα/β-Ser176/180 Antibody, clone 2G2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
bovine, canine, feline, human, monkey, mouse, porcine, rat
Applicazione
affinity binding assay
immunohistochemistry
inhibition assay
western blot
SAB4301429
Anti-phospho-IKK-α/β (pSer180/181) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
western blot
MABF222
Anti-IKKa (p45) Antibody, clone 881H3, clone 881H3, from mouse,
Reattività con
human
Applicazione
immunohistochemistry
immunoprecipitation (IP)
western blot

Proteins

N° Catalogo
Descrizione
Specie
14-461-M
IKKα Protein, active, 10 µg, Active, recombinant full-length human IKKα, containing an N-terminal GST-tag, for use in Kinase Assays.,
Specie
human
SRP5040
IKK α , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EMU041031
MISSION® esiRNA, targeting mouse Chuk,
Specie
mouse
EHU229471
MISSION® esiRNA, targeting human CHUK,
Specie
human

Small Molecule - Substrate

N° Catalogo
Descrizione
Specie
12-459
IKK Substrate Peptide, ,
Specie
human