Passa al contenuto
Merck

CD59

CD59 molecule, complement regulatory protein

Sinonimi:
16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20
Specie:
ID UniProtKB:
ID gene:
  • Human(966) Summary: This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Rat(25407) CD59 molecule, complement regulatory protein
  • Zebrafish(335928) CD59 molecule, complement regulatory protein
  • chicken(423148) CD59 molecule, complement regulatory protein
  • cow(505574) CD59 molecule, complement regulatory protein
  • domestic cat(101092210) CD59 molecule, complement regulatory protein
  • dog(475945) CD59 molecule, complement regulatory protein
  • sheep(101102670) CD59 molecule, complement regulatory protein
  • Domestic Rabbit(100009459) CD59 molecule, complement regulatory protein
  • naked mole-rat(101726814) CD59 molecule, complement regulatory protein

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

N° Catalogo
Descrizione
Specie
Human CD59 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-CD59 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-CD59 Antibody, clone 2/24, FITC conjugated, clone 2/24, Chemicon®, from mouse,
Reattività con
human
Applicazione
flow cytometry
immunofluorescence
Anti-CD59 Antibody, clone 2/24, clone 2/24, Chemicon®, from mouse,
Reattività con
human
Applicazione
flow cytometry
immunofluorescence
Anti-CD59 antibody produced in rabbit, ,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Monoclonal Anti-CD59 antibody produced in mouse, clone MEM-43/5, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
flow cytometry

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human CD59,
Specie
human