Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.

Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.

Cancer research (2017-08-05)

Yun-Chi Tang, Hui Yuwen, Kaiying Wang, Peter M Bruno, Kevin Bullock, Amy Deik, Stefano Santaguida, Marianna Trakala, Sarah J Pfau, Na Zhong, Tao Huang, Lan Wang, Clary B Clish, Michael T Hemann, Angelika Amon

PMID28775166

RÉSUMÉ

Aneuploidy, a hallmark of cancer cells, poses an appealing opportunity for cancer treatment and prevention strategies. Using a cell-based screen to identify small molecules that could selectively kill aneuploid cells, we identified the compound

MATÉRIAUX

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Marque

Description du produit

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A9169

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M1177

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EHU126521

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MISSION^® esiRNA, targeting human SGMS1