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Merck

Mitochondria-targeting "Nanoheater" for enhanced photothermal/chemo-therapy.

Biomaterials (2016-12-13)
Si Chen, Qi Lei, Wen-Xiu Qiu, Li-Han Liu, Di-Wei Zheng, Jin-Xuan Fan, Lei Rong, Yun-Xia Sun, Xian-Zheng Zhang
RÉSUMÉ

In this work, mitochondria-targeting gold nanostar (AuNS) and anticarcinogen DOX were co-encapsulated in hyaluronic acid (HA) protective shell for tumor-targeting synergistic photothermal/chemo-therapy. Cationic peptide R

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HBTU, ≥98.0% (T)
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2-Chlorotrityl chloride, ≥97.0% (AT)
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Fmoc-D-Lys(Boc)-OH, 98%
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meso-Tetraphenylporphyrin, BioReagent, suitable for fluorescence, ≥99.0% (HPLC)