Accéder au contenu
Merck

Antihypertensive (2-aminoethyl)thiourea derivatives. 2.

Journal of medicinal chemistry (1980-12-01)
J W Tilley, H Ramuz, F Hefti, M Gerold
RÉSUMÉ

Starting with 2,6-dichlorophenyl isothiocyanate, 1-(2-aminoethyl)-2-cyano-3-(2,6-dichlorophenyl)guanidine (2) was prepared in three steps. In contrast to the corresponding thiourea 1, this compound was essentially inactive as an antihypertensive agent.

MATÉRIAUX
Référence du produit
Marque
Description du produit

Sigma-Aldrich
2,6-Dichlorophenyl isothiocyanate, 97%