Potassium iodide catalyzed simultaneous C3-formylation and N-aminomethylation of indoles with 4-substituted-N,N-dimethylanilines.

Potassium iodide catalyzed simultaneous C3-formylation and N-aminomethylation of indoles with 4-substituted-N,N-dimethylanilines.

Organic & biomolecular chemistry (2012-11-13)

Lan-Tao Li, Hong-Ying Li, Li-Juan Xing, Li-Juan Wen, Peng Wang, Bin Wang

RÉSUMÉ

A one-pot dual functionalization of indoles has been developed. The simultaneous C3-formylation and N-aminomethylation of indoles can be achieved using readily available potassium iodide as a catalyst and tert-butyl peroxybenzoate as a co-oxidant.

MATÉRIAUX

Référence du produit

Marque

Description du produit

221945

Sigma-Aldrich

Iodure de potassium, ACS reagent, ≥99.0%

207969

Sigma-Aldrich

Iodure de potassium, ReagentPlus^®, 99%

30315

Sigma-Aldrich

Iodure de potassium, puriss. p.a., reag. ISO, reag. Ph. Eur., ≥99.0%

651818

Sigma-Aldrich

Gold etchant, standard

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Sigma-Aldrich

Iodure de potassium, puriss., meets analytical specification of Ph. Eur. BP, USP, 99.0-100.5% (calc. to the dried substance)

204102

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Iodure de potassium, ≥99.99% trace metals basis

60399

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236233

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N-Methylaniline, ≥99%

M29304

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N-Methylaniline, 98%

P8166

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Iodure de potassium, suitable for plant cell culture

429422

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Iodure de potassium, AnhydroBeads^™, −10 mesh, 99.998% trace metals basis

P2963

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Iodure de potassium, BioXtra, ≥99.0%

60422

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Iodure de potassium, tested according to Ph. Eur.

209872

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4-tert-Butyl-N,N-dimethylaniline, 98%

03124-M

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Iodure de potassium, puriss., meets analytical specification of Ph. Eur. BP, USP, 99.0-100.5% (calc. to the dried substance)

65760

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N-Methylaniline, purum, ≥98.0% (GC)

49636

Supelco

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