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1609002

USP

Salicylic acid

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

2-Hydroxybenzoic acid

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About This Item

Formule linéaire :
2-(HO)C6H4CO2H
Numéro CAS:
69-72-7
Poids moléculaire :
138.12
Beilstein:
774890
Numéro MDL:
MFCD00002439
ID de substance PubChem :
329751068

Qualité

pharmaceutical primary standard

Densité de vapeur

4.8 (vs air)

Pression de vapeur

1 mmHg ( 114 °C)

Famille d'API

salicylic acid

Fabricant/nom de marque

USP

pb

211 °C (lit.)

Pf

158-161 °C (lit.)

Solubilité

alcohol: freely soluble
benzene: slightly soluble
boiling water: soluble
chloroform: sparingly soluble
ether: freely soluble
toluene: slightly soluble
water: slightly soluble

Densité

1.44 g/cm3 at 20 °C

Application(s)

pharmaceutical (small molecule)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Salicylic acid USP reference standard for use in specified quality tests and assays.

Also used to prepare standard solutions for the assay, impurity analysis, and performance test by using liquid chromatography in conjunction with a UV detector according to the given below monographs of United States Pharmacopeia (USP) :
  • Salicylic Acid
  • Methyl Salicylate
  • Magnesium Salicylate Tablets
  • Aspirin Boluses

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

USP issued SDS can be found here.
Sales restrictions may apply.

Pictogrammes

CorrosionExclamation markHealth hazard
GHS05,GHS07,GHS08

Mention d'avertissement

Danger

Mentions de danger

H302 - H318 - H361d

Classification des risques

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

Code de la classe de stockage

13 - Non Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

314.6 °F - closed cup

Point d'éclair (°C)

157 °C - closed cup

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Certificats d'analyse (COA)

Lot/Batch Number

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Salicylic acid puriss. p.a., ≥99.0% (T)

Sigma-Aldrich

84210

Salicylic acid

Salicylamide United States Pharmacopeia (USP) Reference Standard

USP

1608000

Salicylamide

Salicylic acid ≥99%, FG

Sigma-Aldrich

W398500

Salicylic acid

Salicylic acid ReagentPlus®, ≥99%

Sigma-Aldrich

105910

Salicylic acid

Acide salicylique EMPROVE® ESSENTIAL Ph Eur,BP,USP

SAFC

1.00631

Acide salicylique

Acetylsalicylic acid for peak identification European Pharmacopoeia (EP) Reference Standard

Y0001460

Acetylsalicylic acid for peak identification

Methyl Salicylate
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(3) (2021)
Andrea Clavijo McCormick et al.
Plant, cell & environment, 37(8), 1909-1923 (2014-01-30)
After herbivory, plants release volatile organic compounds from damaged foliage as well as from nearby undamaged leaves that attract herbivore enemies. Little is known about what controls the volatile emission differences between damaged and undamaged tissues and how these affect
Gary Loake et al.
Current opinion in plant biology, 10(5), 466-472 (2007-10-02)
Salicylic acid (SA) is synthesised by plants in response to challenge by a diverse range of phytopathogens and is essential to the establishment of both local and systemic-acquired resistance (SAR). SA application induces accumulation of pathogenesis-related (PR) proteins. Mutations leading
Caroline Gutjahr et al.
Molecular plant-microbe interactions : MPMI, 22(7), 763-772 (2009-06-16)
Work on the interaction of aerial plant parts with pathogens has identified the signaling molecules jasmonic acid (JA) and salicylic acid (SA) as important players in induced defense of the plant against invading organisms. Much less is known about the
Jyoti Shah
Current opinion in plant biology, 6(4), 365-371 (2003-07-23)
Salicylic acid is an important signal molecule in plant defense. In the past two years, significant progress has been made in understanding the mechanism of salicylic-acid biosynthesis and signaling in plants. A pathway similar to that found in some bacteria
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Protocoles

HPLC Analysis of Aspirin and Salicylic Acid on Ascentis® Express RP-Amide

Separation of Acetylsalicylic acid, analytical standard; Salicylic acid, BioXtra, ≥99.0%

HPLC Analysis of Salicylic Acid and Acetylsalicylic Acid (Aspirin) on Ascentis® Express OH5

Separation of Salicylic acid, meets analytical specification of Ph. Eur., BP, USP, 99.5-100.5% (calc. to the dried substance); Acetylsalicylic acid, purum, ≥99.0% (HPLC)

HPLC Analysis of Benzoic Acid and Related Compounds on Ascentis® RP-Amide

Separation of 4-Hydroxybenzoic acid; Acetylsalicylic acid; Benzoic acid; Salicylic acid; Ethyl 4-hydroxybenzoate

HPLC Analysis of Benzoic Acid Derivatives on Ascentis® C18

HPLC Analysis of Benzoic Acid Derivatives on Ascentis® C18

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