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Documents

P2130000

Piroxicam

Name: Piroxicam
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

4-Hydroxy-2-methyl-3-(pyrid-2-yl-carbamoyl)-2H-1,2-benzothiazine 1,1-dioxide

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About This Item

Formule empirique (notation de Hill):

C₁₅H₁₃N₃O₄S

Numéro CAS:

36322-90-4

Poids moléculaire :

331.35

Numéro MDL:

MFCD00057317

Code UNSPSC :

41116107

ID de substance PubChem :

329820119

Nomenclature NACRES :

NA.24

Qualité

pharmaceutical primary standard

Famille d'API

piroxicam

Fabricant/nom de marque

EDQM

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES

CN1C(C(=O)Nc2ccccn2)=C(O)c3ccccc3S1(=O)=O

InChI

1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)

Clé InChI

QYSPLQLAKJAUJT-UHFFFAOYSA-N

Informations sur le gène

human ... PTGS1(5742) , PTGS2(5743)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Piroxicam EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Cyclooxygenase inhibitor.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit

Description

Tarif

1544541

1544574

1544600

1544520

1544519

2-Aminopyridine, United States Pharmacopeia (USP) Reference Standard

Pictogrammes

GHS06,GHS08

Mention d'avertissement

Danger

Mentions de danger

H301,H373

Conseils de prudence

P260 - P264 - P270 - P301 + P310 - P314 - P405

Classification des risques

Acute Tox. 3 Oral - STOT RE 2 Oral

Organes cibles

Gastrointestinal tract

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Effects of phonophoresis of piroxicam and ultrasound on symptomatic knee osteoarthritis.

Wanwadee Luksurapan et al.

Archives of physical medicine and rehabilitation, 94(2), 250-255 (2012-10-16)

To compare the effects of phonophoresis of piroxicam (PhP) and ultrasound therapy (UT) in patients with mild to moderate, symptomatic knee osteoarthritis (OA). A randomized, double-blind, controlled trial. Department of rehabilitation medicine, university hospital. Patients with knee OA (N=46; mean

Solid-state dependent dissolution and oral bioavailability of piroxicam in rats.

Andres Lust et al.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(1-2), 47-54 (2012-10-23)

The aim of this study was to gain understanding about the effects of different solid-state forms of a poorly water-soluble piroxicam on drug dissolution and oral bioavailability in rats. Three different solid-state forms of piroxicam were studied: anhydrate I (AH)

Fast-track to a solid dispersion formulation using multi-way analysis of complex interactions.

Jian X Wu et al.

Journal of pharmaceutical sciences, 102(3), 904-914 (2012-12-06)

Several factors with complex interactions influence the physical stability of solid dispersions, thus highlighting the need for efficient experimental design together with robust and simple multivariate model. Design of Experiments together with ANalysis Of VAriance (ANOVA) model is one of

A novel extraction technique based on carbon nanotubes reinforced hollow fiber solid/liquid microextraction for the measurement of piroxicam and diclofenac combined with high performance liquid chromatography.

Xin-Yue Song et al.

Talanta, 100, 153-161 (2012-11-13)

A novel design of carbon nanotubes reinforced hollow fiber solid/liquid phase microextraction (CNTs-HF-SLPME) was developed to determine piroxicam and diclofenac in different real water samples. Functionalized multi-walled carbon nanotubes (MWCNTs) were held in the pores of hollow fiber with sol-gel

Nematode asparaginyl-tRNA synthetase resolves intestinal inflammation in mice with T-cell transfer colitis.

Michael A Kron et al.

Clinical and vaccine immunology : CVI, 20(2), 276-281 (2012-12-21)

The therapeutic effects of a controlled parasitic nematode infection on the course of inflammatory bowel disease (IBD) have been demonstrated in both animal and human models. However, the inability of individual well-characterized nematode proteins to recreate these beneficial effects has

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