M2772

Menthol

99%

• Synonyme(s) : 2-Isopropyl-5-methylcyclohexanol, Hexahydrothymol
• Formule empirique (notation de Hill): C₁₀H₂₀O
• Numéro CAS: 89-78-1
• Poids moléculaire : 156.27
• Numéro Beilstein : 3194263
• Numéro CE : 201-939-0
• Numéro MDL: MFCD00001484
• Code UNSPSC : 12352212
• ID de substance PubChem : 24896764
• Nomenclature NACRES : NA.25

Propriétés

• Pression de vapeur: 0.8 mmHg ( 20 °C)
• Niveau de qualité: 200
• Pureté: 99%
• Point d'ébullition: 216 °C (lit.)
• Pf: 34-36 °C (lit.)
• Densité: 0.89 g/mL at 25 °C (lit.)
• Application(s): metabolomics; vitamins, nutraceuticals, and natural products
• Chaîne SMILES: CC(C)C1CCC(C)CC1O
• InChI: 1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3
• Clé InChI: NOOLISFMXDJSKH-UHFFFAOYSA-N
• Informations sur le gène: human ... TRPA1(8989) , TRPM8(79054)

Description

Description générale

Menthol (C₁₀H₂₀O) is a terpenoid compound. It is extracted from the plants belonging to Mentha genus in the Lamiaceae family.

Menthol is a cyclic monoterpene alcohol, which is extracted from essential oils of Mentha canadensis and Mentha x piperita. It possesses antimicrobial, anticancer and anti-inflammatory properties. Menthol acts as a transient receptor potential cation channel (TRPM8) agonist. It also exhibits analgesic, antipruritic, anesthetic and cooling effects.

Application

Menthol has been used:

• to test its antifungal susceptibility
• to determine its efficacy as an anesthetic in fish
• to activate transient receptor potential cation channel (TRPM8)
• as an odorant for measuring sniffing dynamics

Actions biochimiques/physiologiques

Menthol exhibits antifungal action on the membrane permeability and the cell wall consistency, this might leads to cell death or inhibition of the C. albicans filamentation. Therefore, it can be used as a potential therapeutic agent for candidiasis. In addition to antifungal activity, menthol also exhibits anesthetic, antispasmodic, anti-ulcer and antiviral properties. It is considered as a safe compound for animal life. Therefore, Menthol is widely used in pharmaceuticals, cosmetics and food industries.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319
• Conseils de prudence: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 204.8 °F
• Point d'éclair (°C): 96 °C
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves