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4-aminobiphényl

analytical standard

Synonyme(s) :

4-biphénylamine

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About This Item

Formule linéaire :
C6H5C6H4NH2
Numéro CAS:
Poids moléculaire :
169.22
Numéro Beilstein :
386533
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

Température d'inflammation spontanée

842 °F

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Point d'ébullition

191 °C/15 mmHg (lit.)

Pf

52-54 °C (lit.)

Application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

Format

neat

Chaîne SMILES 

Nc1ccc(cc1)-c2ccccc2

InChI

1S/C12H11N/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H,13H2

Clé InChI

DMVOXQPQNTYEKQ-UHFFFAOYSA-N

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Description générale

4-Aminobiphenyl is classified under the aromatic amine group of compounds.

Application

4-Aminobiphenyl has been used as an analytical reference standard for the analysis of 4-aminobiphenyl in food packaging materials by liquid chromatography-full scan-high resolution mass spectrometry (LC-HRMS).
It may be used as an analytical reference standard for the determination of 4-aminobiphenyl in:
  • Particulate phase mainstream cigarette smoke samples by solid-phase extraction (SPE) and gas chromatography coupled to MS equipped with selected ion monitoring (SIM) mode of detection as well as simultaneous distillation and extraction (SDE) and GC-MS with SIM detection.
  • Environmental water samples by hollow fiber-liquid phase microextraction (HF-LPME) and microemulsion electrokinetic chromatography (MEEKC).
  • Indoor and outdoor air samples by GC-MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogrammes

Health hazardExclamation mark

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 4 Oral - Carc. 1A

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

235.4 °F - closed cup

Point d'éclair (°C)

113 °C - closed cup

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Simultaneous determination of aliphatic and aromatic amines in indoor and outdoor air samples by gas chromatography-mass spectrometry.
Akyuz M.
Talanta, 71(1), 486-492 (2007)
Analysis of polycyclic aromatic hydrocarbons, phenols and aromatic amines in particulate phase cigarette smoke using simultaneous distillation and extraction as a sole sample clean-up step.
Forehand JB, et al.
Journal of Chromatography A, 898(1), 111-124 (2000)
Samuel M Cohen et al.
Critical reviews in toxicology, 36(10), 803-819 (2006-11-23)
The IPCS Human Relevance Framework was evaluated for a DNA-reactive (genotoxic) carcinogen, 4-aminobiphenyl, based on a wealth of data in animals and humans. The mode of action involves metabolic activation by N-hydroxylation, followed by N-esterification leading to the formation of
Moinuddin et al.
Environmental toxicology, 29(5), 568-576 (2012-05-23)
4-Aminobiphenyl (4-ABP), an aromatic amine is a major environmental carcinogen found mainly in cigarette smoke. It has been vastly implicated in mutagenesis and cancer development. In this study, commercially available human placental DNA was exposed to 4-ABP (1.3 mM) in
Determination of aromatic amines in environmental water sample by hollow fiber-liquid phase microextraction and microemulsion electrokinetic chromatography.
Lin Z, et al.
Journal of Chromatography A, 1217(26), 4507-4510 (2010)

Protocoles

US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on Equity®-5 (30 m x 0.25 mm I.D., 0.50 μm)

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