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00190585

Hypericin

primary reference standard

Synonyme(s) :

4,5,7,4′,5′,7′-Hexahydroxy-2,2′-dimethylnaphthodianthrone

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About This Item

Formule empirique (notation de Hill):
C30H16O8
Numéro CAS:
548-04-9
Poids moléculaire :
504.44
Numéro Beilstein :
1917913
Numéro CE :
208-941-0
Numéro MDL:
MFCD00016683
Code UNSPSC :
85151701
ID de substance PubChem :
329747015
Nomenclature NACRES :
NA.24

Qualité

primary reference standard

Durée de conservation

limited shelf life, expiry date on the label

Fabricant/nom de marque

HWI

Température de stockage

−20°C

Chaîne SMILES 

Cc1cc(O)c2C(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6C(=O)c7c(O)cc(C)c8c1c2c(c34)c(c78)c56

InChI

1S/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,31-36H,1-2H3

Clé InChI

BTXNYTINYBABQR-UHFFFAOYSA-N

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Catégories apparentées

Description générale

Produced by HWI Analytik
Exact content can be found on the certificate

Application

It was used as reference standard in determining hypericins in St. John′s Wort using HPLC method.
Reference standard in the analysis of herbal medicinal products.

Autres remarques

This compound is commonly found in plants of the genus: hypericum

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
HWI02819-1
HWI02819
HWI02062-1
HWI02062
HWI01814-2

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D E Gray et al.
Journal of AOAC International, 83(4), 944-949 (2000-09-20)
Hypericin and hyperforin are believed to be among the active constituents in common St. John's wort (Hypericum perforatum L.). Presently, dietary supplements are generally standardized to contain specified levels of hypericin and hyperforin, and the related compounds, pseudohypericin and adhyperforin.
J B Hudson et al.
Antiviral research, 15(2), 101-112 (1991-02-01)
Hypericin, a photodynamic plant quinone, readily inactivated murine cytomegalovirus (MCMV), Sindbis virus, and human immunodeficiency virus type 1 (HIV-1), especially on exposure to fluorescent light. Sindbis virus was significantly more sensitive than MCMV. The inactivated MCMV, when used to infect
Theodossis A Theodossiou et al.
Molecular pharmaceutics, 6(6), 1775-1789 (2009-09-11)
Photodynamic therapy (PDT) is an established anticancer treatment employing a phototoxin (photosensitizer), visible light and oxygen. The latter is photochemically converted into reactive oxygen species, which are highly toxic to the cells. Hypericin, a natural pigment of hypericum plants, is
Pavol Miskovsky
Current drug targets, 3(1), 55-84 (2002-03-20)
Hypericin, a naturally occurring pigment, is found in certain species of plants from the genus Hypericum, the most common of which is Saint John's Wort (Hypericum perforatum). Recent interest in hypericin is provoked by the discovery that it possesses extremely
Tobias Kiesslich et al.
Current medicinal chemistry, 13(18), 2189-2204 (2006-08-22)
During the last decades, Photodynamic Therapy (PDT) has been established as a powerful alternative approved by health agencies of several countries for treatment of various malignant and some non-malignant diseases. PDT makes use of the light-induced destruction of target cells
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