HC19SERA1-85K

MILLIPLEX^® SARS-CoV-2 Antigen Panel 1 IgA

Propriétés

• Espèces réactives: human
• Fabricant/nom de marque: Milliplex^®
• Technique(s): multiplexing: suitable
• Méthode de détection: fluorometric (Luminex^® xMAP^®)
• Température de stockage: 2-8°C

Description

Description générale

"The SARS-CoV-2 coronavirus is the pathogenic cause of the human disease COVID-19. The virus particle consists of RNA encapsulated by the nucleocapsid (N) protein which is enveloped by a membrane (M) protein. The corona-like spike proteins surrounding this inner core consist of subunits S1, S2 and the receptor binding domain which binds to the human cellular ACE-2 receptor. Upon binding, the virus enters the cell, takes over the cellular machinery, reproduces, and the viral contagion continues. Viral structural proteins offer antigenic potential for an immune response. Upon viral infection the humoral immune system responds first by producing the immunoglobulin IgM, followed later by IgG which can convey long lasting immunity. IgA, a mucosal immune response, is also found in blood.By testing for IgM, IgG, and IgA in human serum and plasma, researchers may identify those who have been exposed to the SARS-CoV-2 virus and mounted some level of immune response. Researchers may further understand the immune response over the course of infection and recovery from COVID-19."MILLIPLEX^® SARS-CoV-2 Antigen Panel 1 IgA is a 4-plex kit to be used for the simultaneous analysis of human serum or plasma samples for IgA antibodies which recognize any or all of the following analytes: SARS-CoV-2 Spike S1, SARS-CoV-2 Spike S2, SARS-Cov-2 RBD, Sars-CoV-2 N.

Application

The SARS-CoV-2 Antigen Panel 1 IgA is a bead-based multiplex assay based on the Luminex^® xMAP technology which enables the simultaneous analysis of human samples for IgA antibodies which recognize any of the following analytes: SARS-CoV-2 Spike S1, SARS-CoV-2 Spike S2, SARS-Cov-2 RBD, Sars-CoV-2 N. This is assay yields results in Median Fluorescence Intensity (MFI).Four assay control beads are included in the base kit.This is a one day assay.This assay requires 25 μL of 1:100 diluted plasma or serum.Analytes available:SARS-CoV-2 Nucleocapsid Protein (N);SARS-CoV-2 Receptor Binding Domain (RBD);SARS-CoV-2 Spike Protein Subunit 1 (S1);SARS-CoV-2 Spike Protein Subunit 2 (S2)

Caractéristiques et avantages

Design your multiplex kit by choosing available analytes within this panel.

Conditionnement

96-well plate

Stockage et stabilité

Recommended storage for kit components is 2 - 8°C.

Informations légales

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Pictogrammes: GHS07,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H317 - H319 - H411
• Conseils de prudence: P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable