495417-M

N-Oleoyl Ethanolamine

A potent inhibitor of the ceramidase found in human kidney and cerebellum.

• Synonyme(s) : N-Oleoyl Ethanolamine, N-2-Hydroxyethyl-9(Z)-octadecenamide, AC Inhibitor I, Acid Ceramidase Inhibitor I, OEA
• Formule empirique (notation de Hill): C₂₀H₃₉NO₂
• Numéro CAS: 111-58-0
• Poids moléculaire : 325.53
• Numéro MDL: MFCD00045972
• Code UNSPSC : 12352211

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98% (TLC)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Couleur: white
• Solubilité: chloroform: 5 mg/mL; ethanol: 5 mg/mL; methanol: 5 mg/mL
• Température de stockage: −20°C
• InChI: 1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
• Clé InChI: BOWVQLFMWHZBEF-KTKRTIGZSA-N

Description

Description générale

A potent inhibitor of the ceramidase found in human kidney and cerebellum. A specific inhibitor of acid ceramidase (IC₅₀ ~ 500 µM).

A potent inhibitor of the ceramidase found in human kidney and cerebellum. Blocks the conversion of ceramide to sphingosine. A specific inhibitor of acid ceramidase (IC₅₀ ~ 500 µM).

Actions biochimiques/physiologiques

Primary Target
Acid ceramidase

Target IC₅₀: ~ 500 µM against acid ceramidase

Avertissement

Toxicity: Standard Handling (A)

Autres remarques

Pahan, K., et al. 1998. J. Biol. Chem. 273, 2591.
Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
Sugita, M., et al. 1975. Biochim. Biophys. Acta398, 125.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable