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Merck
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Key Documents

07-001

Sigma-Aldrich

Anti-p47-phox Antibody

serum, Upstate®

Synonyme(s) :

Anti-Anti-CGD1, Anti-Anti-NCF1A, Anti-Anti-NOXO2, Anti-Anti-SH3PXD1A, Anti-Anti-p47phox

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

serum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

human

Fabricant/nom de marque

Upstate®

Technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotype

IgG

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... NCF1(653361)

Spécificité

Recognizes p47 phox.

Immunogène

GST fusion protein corresponding to full-length human p47-phox

Application

Anti-p47-phox Antibody detects level of p47-phox & has been published & validated for use in IC, IP & WB.
Research Category
Neuroscience
Research Sub Category
Oxidative Stress

Qualité

routinely evaluated by immunoblot on RIPA lysates from HL-60 cells

Description de la cible

47 kDa

Forme physique

Immunoaffinity Purified immunoglobulin in 0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, 5mg/ml BSA before the addition of glycerol to 30%
Unpurified

Stockage et stabilité

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Remarque sur l'analyse

Control
HL-60 cell lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

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Journal of Agricultural and Food Chemistry null
Molecular diagnosis of X-linked chronic granulomatous disease in Iran.
S Teimourian, Z Rezvani, M Badalzadeh, C Kannengiesser, D Mansouri, M Movahedi et al.
International Journal of Hematology null
Y Li et al.
Redox biology, 22, 101143-101143 (2019-03-22)
First described as essential to the phagocytic activity of leukocytes, Nox2-derived ROS have emerged as mediators of a range of cellular and tissue responses across species from salubrious to deleterious consequences. Knowledge of their role in inflammation is limited, however.
Eduardo Rebelato et al.
Life sciences, 91(7-8), 244-249 (2012-07-24)
NADPH oxidase (NOX) is a known source of superoxide anions in phagocytic and non-phagocytic cells. In this study, the presence of this enzyme in human pancreatic islets and the importance of NADPH oxidase in human β-cell function were investigated. In
Dena Parsa et al.
Molecular medicine (Cambridge, Mass.), 28(1), 60-60 (2022-06-07)
African Americans (AAs) are disproportionately affected by cardiovascular disease (CVD), they are 20% more likely to die from CVD than whites, chronic exposure to inflammation and oxidative stress contributes to CVD. In previous studies, enhancing parasympathetic cholinergic activity has been

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