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Key Documents

840635P

Avanti

12:0 PA

1,2-dilauroyl-sn-glycero-3-phosphate (sodium salt), powder

Synonyme(s) :

1,2-didodecanoyl-sn-glycero-3-phosphate (sodium salt); DLPA; PA(12:0/12:0)

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About This Item

Formule empirique (notation de Hill):
C27H52O8PNa
Numéro CAS:
Poids moléculaire :
558.66
Code UNSPSC :
51191904
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 200 mg (840635P-200mg)
pkg of 1 × 25 mg (840635P-25mg)

Fabricant/nom de marque

Avanti Research - A Croda Brand 840635P

Type de lipide

phospholipids
cardiolipins

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[H][C@@](COP([O-])(O)=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[Na+]

InChI

1S/C27H53O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-26(28)33-23-25(24-34-36(30,31)32)35-27(29)22-20-18-16-14-12-10-8-6-4-2;/h25H,3-24H2,1-2H3,(H2,30,31,32);/q;+1/p-1/t25-;/m1./s1

Clé InChI

CIOHBYXGWWPOIS-VQIWEWKSSA-M

Description générale

12:0 PA (1,2-dilauroyl-sn-glycero-3-phosphate) is a sodium salt of modified lipid, wherein C-1, C-2 of glycerol is substituted with didodecanoyl and C-3 of glycerol is substituted with phosphatidic acid group.

Application

12:0 PA (1,2-dilauroyl-sn-glycero-3-phosphate (sodium salt)) has been used as an internal lipid standard in the matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry (MALDI FT-ICR MS) analysis. It may be used as a lipid standard:
  • for the quantification of phospholipids by high-performance liquid chromatography coupled to tandem mass spectrometryelectrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS)
  • for the quantification of lipids in cold-pressed rapeseed oils based on direct infusion electrospray ionization tandem mass spectrometry
  • in liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis

Actions biochimiques/physiologiques

Phosphatidic acid (PA) might serve as a modulator of phagocyte respiratory burst.

Conditionnement

5 mL Amber Glass Screw Cap Vial (840635P-200mg)
5 mL Amber Glass Screw Cap Vial (840635P-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Marie Garnier-Lhomme et al.
PloS one, 4(1), e4255-e4255 (2009-01-24)
The cytoplasm of eukaryotic cells is a highly dynamic compartment where membranes readily undergo fission and fusion to reorganize the cytoplasmic architecture, and to import, export and transport various cargos within the cell. The double membrane of the nuclear envelope
Ya Xie et al.
Food chemistry, 285, 194-203 (2019-02-25)
Microwave pretreatment of rapeseeds prior to cold-pressing is a simple and desirable method for producing high quality oils. In this study, a rapid and sensitive lipid profiling platform employing an accurate quantification strategy was established based on direct infusion electrospray
Yuchen Sun et al.
Metabolites, 9(11) (2019-11-07)
Extracellular vesicles (EVs) consist of lipid bilayers, occur in various biofluids, and are invaluable in biomarker screening. Liquid chromatography coupled with high-resolution mass spectrometry (LC-MS) was recently used to study comprehensive EV lipid profiles in vitro. The aim of this
Emily R Schenk et al.
Journal of mass spectrometry : JMS, 50(1), 88-94 (2015-01-21)
Bacterial resistance to antibiotics has become an increasing threat, requiring not only the development of new targets in drug discovery, but more importantly, a better understanding of cellular response. In the current study, three closely related Escherichia coli strains, a
Yasunori Watanabe et al.
Nature communications, 6, 7922-7922 (2015-08-04)
Eukaryotic cells are compartmentalized into membrane-bounded organelles whose functions rely on lipid trafficking to achieve membrane-specific compositions of lipids. Here we focused on the Ups1-Mdm35 system, which mediates phosphatidic acid (PA) transfer between the outer and inner mitochondrial membranes, and

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