399337

Benzamide

purified by sublimation, ≥99.5%

• Synonyme(s) : Benzoic acid amide
• Formule linéaire : C₆H₅CONH₂
• Numéro CAS: 55-21-0
• Poids moléculaire : 121.14
• Numéro Beilstein : 385876
• Numéro CE : 200-227-7
• Numéro MDL: MFCD00007968
• Code UNSPSC : 12352100
• ID de substance PubChem : 24864807
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: ≥99.5%
• Forme: powder
• Produit purifié par: sublimation
• Pf: 125-128 °C (lit.)
• Solubilité: ethanol: soluble 50 mg/mL, clear to slightly hazy, colorless to light yellow
• Chaîne SMILES: NC(=O)c1ccccc1
• InChI: 1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)
• Clé InChI: KXDAEFPNCMNJSK-UHFFFAOYSA-N
• Informations sur le gène: human ... PARP1(142)

Description

Description générale

Benzamide (Benzoic acid amide, BA) is an amide of benzoic acid. BA on crystallization in benzene (solvent) affords crystals suitable for X-ray analysis. Crystal structure studies suggest that its crystals are monoclinic having space group P2₁/c. Kinetics and mechanism of its reaction with hydrogen peroxide have been proposed.

Application

Benzamide was used to study the mechanism of photocatalytic decomposition of aqueous solution of acetic acid, acetamide and acetonitrile in the presence of semiconductors. Benzamide was used to develop a robust screening method to study biotransformations using (+)-γ-lactamase enzyme.

Actions biochimiques/physiologiques

Inhibits poly(ADP-ribose) polymerase (PARP).

Informations sur la sécurité

• Pictogrammes: GHS08,GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302,H341
• Conseils de prudence: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Classification des risques: Acute Tox. 4 Oral - Muta. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 356.0 °F - closed cup
• Point d'éclair (°C): 180 °C - closed cup
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves