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Merck

WISP3

WNT1 inducible signaling pathway protein 3

Synonymes:
CCN6, LIBC, PPAC, PPD
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(8838) Summary: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(327743) WNT1 inducible signaling pathway protein 3
  • Rat(499461) WNT1 inducible signaling pathway protein 3
  • domestic guinea pig(100727845) WNT1 inducible signaling pathway protein 3
  • naked mole-rat(101697161) WNT1 inducible signaling pathway protein 3
  • cow(100849041) WNT1 inducible signaling pathway protein 3
  • cow(784564) WNT1 inducible signaling pathway protein 3
  • sheep(101109099) WNT1 inducible signaling pathway protein 3
  • Zebrafish(794092) WNT1 inducible signaling pathway protein 3
  • chicken(770827) WNT1 inducible signaling pathway protein 3
  • Horse(100072430) WNT1 inducible signaling pathway protein 3
  • domestic cat(101086230) WNT1 inducible signaling pathway protein 3
  • dog(100686448) WNT1 inducible signaling pathway protein 3

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-WISP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-WISP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence

Proteins

Référence du produit
Description
Espèce(s)
WISP-3 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Wisp3,
Espèce(s)
mouse
MISSION® esiRNA, targeting human WISP3,
Espèce(s)
human