UBE2D2
ubiquitin-conjugating enzyme E2D 2
Synonymes:
E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B
Espèce(s):
Human UBE2D2 (7322), Rat Ube2d2 (641452), chicken UBE2D2 (416137), domestic cat UBE2D2 (101092081), dog UBE2D2 (612742), domestic guinea pig Ube2d2 (100732779), naked mole-rat Ube2d2 (101724153), cow UBE2D2 (541003)
ID UniProtKB:
ID du gène:
- Human(7322) Summary: Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
- Rat(641452) ubiquitin-conjugating enzyme E2D 2
- chicken(416137) ubiquitin-conjugating enzyme E2D 2
- domestic cat(101092081) ubiquitin-conjugating enzyme E2D 2
- dog(612742) ubiquitin-conjugating enzyme E2D 2
- domestic guinea pig(100732779) ubiquitin-conjugating enzyme E2D 2
- naked mole-rat(101724153) ubiquitin-conjugating enzyme E2D 2
- cow(541003) ubiquitin-conjugating enzyme E2D 2
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-UBE2D2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Référence du produit
Description
Espèce(s)
UbcH5b Conjugating Enzyme, 100 µg, The His6-tagged fusion protein of UbcH5b is charge & support ubiquitinylation in vitro. The His6-tagged UbcH5 family members all appear to form thiol ester conjugates with ubiquitin at a similar rate under similar conditions.,
Espèce(s)
human
esiRNA
Référence du produit
Description
Espèce(s)