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Merck

TPO

thyroid peroxidase

Synonymes:
MSA, TDH2A, TPX
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(7173) Summary: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
  • Mouse(22018) thyroid peroxidase
  • Rat(54314) thyroid peroxidase
  • cow(525013) thyroid peroxidase
  • naked mole-rat(101704548) thyroid peroxidase
  • domestic guinea pig(100723704) thyroid peroxidase
  • chicken(776120) thyroid peroxidase
  • domestic cat(101098706) thyroid peroxidase
  • dog(403521) thyroid peroxidase

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ELISA

Référence du produit
Description
Espèce(s)
Human TPO / Thyroid Peroxidase ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-TPO antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry

western blot
Anti-TPO (Thyroid Peroxidase) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM368, purified immunoglobulin,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-TPO antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-TPO antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-TPO (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
canine, guinea pig, horse, human, mouse, pig, rabbit, rat
Application
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Methimazole, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Methimazole, analytical standard,
Espèce(s)
human
Methimazole, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Methimazole, VETRANAL®, analytical standard,
Espèce(s)
human
2-Mercapto-1-methylimidazole, ≥99%,
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
Thrombopoietin, TPO (Thrombopoietin, Mpl-ligand, MGDF) stimulates the proliferation & maturation of megakaryocytes & promotes increased circulating levels of platelets in vivo.,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human TPO,
Espèce(s)
human