TNNI2
troponin I type 2 (skeletal, fast)
Synonymes:
AMCD2B, DA2B, FSSV, fsTnI
Espèce(s):
Human TNNI2 (7136), Mouse Tnni2 (21953), Rat Tnni2 (29389), chicken TNNI2 (396386), dog TNNI2 (475995), naked mole-rat Tnni2 (101717320), Domestic Rabbit TNNI2 (100009581), domestic guinea pig Tnni2 (100722531), cow TNNI2 (506434), sheep TNNI2 (101121135)
ID UniProtKB:
ID du gène:
- Human(7136) Summary: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
- Mouse(21953) troponin I, skeletal, fast 2
- Rat(29389) troponin I type 2 (skeletal, fast)
- chicken(396386) troponin I type 2 (skeletal, fast)
- dog(475995) troponin I type 2 (skeletal, fast)
- naked mole-rat(101717320) troponin I type 2 (skeletal, fast)
- Domestic Rabbit(100009581) troponin I type 2 (skeletal, fast)
- domestic guinea pig(100722531) troponin I type 2 (skeletal, fast)
- cow(506434) troponin I type 2 (skeletal, fast)
- sheep(101121135) troponin I type 2 (skeletal, fast)
- cow(790768) troponin I, fast skeletal muscle-like
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Référence du produit
Description
Espèce(s)
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-TNNI2 antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
bovine, dog, goat, guinea pig, horse, human, rabbit, rat
Application
western blot
Anti-TNNI2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TNNI2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse
Application
western blot