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Merck

TNFRSF10C

tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

Synonymes:
CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID
Espèce(s):
Human TNFRSF10C (8794)
ID UniProtKB:
O14798, O14755, Q08AS6, Q6FH98, Q6UXM5
ID du gène:
  • Human(8794) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]

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ELISA

Référence du produit
Description
Espèce(s)
RAB0482
Human TRAIL R3 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
PRS2179
Anti-DCR1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunocytochemistry
western blot
SAB4700535
Monoclonal Anti-CD263, azide free antibody produced in mouse, clone TRAIL-R3-02, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
flow cytometry
SAB4700537
Monoclonal Anti-CD263-PE antibody produced in mouse, clone TRAIL-R3-02, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
flow cytometry
PRS2299
Anti-DCR1 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
SAB4701091
Monoclonal Anti-CD263-APC antibody produced in mouse, clone TRAIL-R3-02,
Espèces réactives
Application
flow cytometry

esiRNA

Référence du produit
Description
Espèce(s)
EHU097041
MISSION® esiRNA, targeting human TNFRSF10C,
Espèce(s)
human