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Merck

SOCS3

suppressor of cytokine signaling 3

Synonymes:
ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(9021) Summary: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]
  • Mouse(12702) suppressor of cytokine signaling 3
  • Rat(89829) suppressor of cytokine signaling 3
  • chicken(395299) suppressor of cytokine signaling 3
  • Horse(100050730) suppressor of cytokine signaling 3
  • domestic cat(101081846) suppressor of cytokine signaling 3
  • dog(442949) suppressor of cytokine signaling 3
  • cow(282081) suppressor of cytokine signaling 3
  • sheep(100294595) suppressor of cytokine signaling 3
  • domestic guinea pig(100725088) suppressor of cytokine signaling 3
  • naked mole-rat(101704157) suppressor of cytokine signaling 3

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-SOCS3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Monoclonal Anti-SOCS3 antibody produced in mouse, clone 2E5, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
Anti-SOCS3 Antibody, clone 1B2, clone 1B2, Upstate®, from mouse,
Espèces réactives
human, mouse
Application
western blot
Monoclonal Anti-SOCS3 antibody produced in mouse, clone 1E4, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
Monoclonal Anti-SOCS3 antibody produced in mouse, clone SO1,
Espèces réactives
human
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human SOCS3,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Socs3,
Espèce(s)
mouse