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Merck

SETD2

SET domain containing 2

Synonymes:
HBP231, HIF-1, HIP-1, HYPB, KMT3A, SET2, p231HBP
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(29072) Summary: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
  • Mouse(235626) SET domain containing 2
  • Rat(316013) SET domain containing 2
  • Zebrafish(794199) SET domain containing 2
  • Horse(100064888) SET domain containing 2
  • domestic cat(101085029) SET domain containing 2
  • dog(476643) SET domain containing 2
  • chicken(420404) SET domain containing 2
  • cow(539860) SET domain containing 2
  • naked mole-rat(101719404) SET domain containing 2
  • domestic guinea pig(100719166) SET domain containing 2

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-SETD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-SETD2 antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-SETD2 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
western blot
Monoclonal Anti-SETD2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9956, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-SETD2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
canine, human, mouse, pig
Application
ELISA
western blot

Proteins

Référence du produit
Description
Espèce(s)
Set2 human, recombinant, expressed in E. coli, ≥75% (SDS-PAGE),
Espèce(s)
human
SETD2 active human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human SETD2,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Setd2,
Espèce(s)
mouse