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Merck

SCN4A

sodium channel, voltage-gated, type IV, alpha subunit

Synonymes:
HOKPP2, HYKPP, HYPP, NAC1A, Na(V)1.4, Nav1.4, SkM1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6329) Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders. [provided by RefSeq, Jul 2008]
  • Mouse(110880) sodium channel, voltage-gated, type IV, alpha
  • Rat(25722) sodium channel, voltage-gated, type IV, alpha subunit
  • domestic guinea pig(100717730) sodium channel, voltage-gated, type IV, alpha subunit
  • naked mole-rat(101713228) sodium channel, voltage-gated, type IV, alpha subunit
  • cow(517426) sodium channel, voltage-gated, type IV, alpha subunit
  • sheep(101123056) sodium channel, voltage-gated, type IV, alpha subunit
  • chicken(771297) sodium channel, voltage-gated, type IV, alpha subunit
  • Horse(100049793) sodium channel, voltage-gated, type IV, alpha subunit
  • domestic cat(101098669) sodium channel, voltage-gated, type IV, alpha subunit
  • dog(610754) sodium channel, voltage-gated, type IV, alpha subunit

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-SCN4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anticorps monoclonal anti-canal sodique, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Espèces réactives
mammals
Application
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

Référence du produit
Description
Espèce(s)
Levobupivacaine hydrochloride, ≥98% (HPLC),
Espèce(s)
human
Ranolazine dihydrochloride, ≥98% (HPLC), powder,
Espèce(s)
human
Lidocaine hydrochloride monohydrate, solid,
Espèce(s)
human
Lidocaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Lidocaine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Scn4a,
Espèce(s)
mouse
MISSION® esiRNA, targeting human SCN4A,
Espèce(s)
human