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Merck

RBM8A

RNA binding motif protein 8A

Synonymes:
BOV-1A, BOV-1B, BOV-1C, C1DELq21.1, DEL1q21.1, MDS014, RBM8, RBM8B, TAR, Y14, ZNRP, ZRNP1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(9939) Summary: This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]
  • Mouse(60365) RNA binding motif protein 8a
  • Rat(295284) RNA binding motif protein 8A
  • Zebrafish(503767) RNA binding motif protein 8A
  • domestic cat(101098563) RNA binding motif protein 8A
  • Horse(100034052) RNA binding motif protein 8A
  • dog(475827) RNA binding motif protein 8A
  • domestic guinea pig(100731698) RNA binding motif protein 8A
  • naked mole-rat(101702668) RNA binding motif protein 8A
  • cow(518045) RNA binding motif protein 8A
  • sheep(101117890) RNA binding motif protein 8A

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-RBM8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anticorps anti-Y14, clone 4C4, clone 4C4, from mouse,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)

western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human RBM8A,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Rbm8a,
Espèce(s)
mouse