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PRMT1

protein arginine methyltransferase 1

Synonymes:
ANM1, HCP1, HRMT1L2, IR1B4
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3276) Summary: This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
  • Mouse(15469) protein arginine N-methyltransferase 1
  • Rat(60421) protein arginine methyltransferase 1
  • Zebrafish(321974) protein arginine methyltransferase 1
  • dog(476411) protein arginine methyltransferase 1
  • domestic cat(101095389) protein arginine methyltransferase 1
  • Horse(100052097) protein arginine methyltransferase 1
  • cow(520388) protein arginine methyltransferase 1
  • domestic guinea pig(100724273) protein arginine methyltransferase 1
  • naked mole-rat(101721462) protein arginine methyltransferase 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PRMT1 Antibody, Upstate®, from rabbit,
Espèces réactives
human, mouse
Application
western blot
Anti-PRMT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
western blot
Anti-PRMT1 antibody, Mouse monoclonal, clone PRMT1-171, purified from hybridoma cell culture,
Espèces réactives
bovine, canine, chicken, hamster, human, monkey, mouse, rat
Application
ELISA
immunoprecipitation (IP)

western blot
Monoclonal Anti-PRMT1 antibody produced in mouse, clone GT10111, affinity isolated antibody,
Espèces réactives
human, mouse
Application
western blot
Monoclonal Anti-PRMT1 antibody produced in mouse, clone GT779, affinity isolated antibody,
Espèces réactives
human, mouse
Application
immunofluorescence
western blot

Proteins

Référence du produit
Description
Espèce(s)
PRMT1 human, recombinant, expressed in E. coli, ≥50% (SDS-PAGE),
Espèce(s)
human
PRMT1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Espèce(s)
human
PRMT1 from rat, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), buffered aqueous solution,
Espèce(s)
rat

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PRMT1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Prmt1,
Espèce(s)
mouse