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PIM1

pim-1 oncogene

Synonymes:
PIM
Espèce(s):
Human PIM1 (5292), Mouse Pim1 (18712), Rat Pim1 (24649), Zebrafish pim1 (58054), domestic cat PIM1 (493888), Horse PIM1 (100053898), chicken PIM1 (100858838), dog PIM1 (481772), cow PIM1 (281402), sheep PIM1 (100272002) ...Plus
ID UniProtKB:
P11309, Q38RT9, Q5T7H7, Q96RG3
ID du gène:
  • Human(5292) Summary: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
  • Mouse(18712) proviral integration site 1
  • Rat(24649) pim-1 oncogene
  • Zebrafish(58054) pim-1 oncogene
  • domestic cat(493888) pim-1 oncogene
  • Horse(100053898) pim-1 oncogene
  • chicken(100858838) pim-1 oncogene
  • dog(481772) pim-1 oncogene
  • cow(281402) pim-1 oncogene
  • sheep(100272002) pim-1 oncogene
  • domestic guinea pig(100724588) pim-1 oncogene
  • naked mole-rat(101706236) pim-1 oncogene

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Antibodies

Référence du produit
Description
Espèces réactives
Application
WH0005292M16
Monoclonal Anti-PIM1 antibody produced in mouse, clone 6A2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
immunohistochemistry
SAB1411967
ANTI-PIM1 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB2104730
Anti-PIM1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Application
western blot
SAB4504055
Anti-phospho-Pim-1 (pTyr309) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
SAB1411965
ANTI-PIM1 antibody produced in mouse, clone 1C12, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot

Proteins

Référence du produit
Description
Espèce(s)
SRP5066
PIM1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EHU900251
MISSION® esiRNA, targeting human PIM1,
Espèce(s)
human
EMU090851
MISSION® esiRNA, targeting mouse Pim1,
Espèce(s)
mouse