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Merck

PGGT1B

protein geranylgeranyltransferase type I, beta subunit

Synonymes:
BGGI, GGTI
Espèce(s):
Human PGGT1B (5229), Mouse Pggt1b (225467), Rat Pggt1b (81746), Zebrafish pggt1b (570808), chicken PGGT1B (770633), domestic cat PGGT1B (101089829), dog PGGT1B (481440), cow PGGT1B (509322), sheep PGGT1B (101123045), domestic guinea pig Pggt1b (100735292)
ID UniProtKB:
P53609, Q5MJP9
ID du gène:
  • Human(5229) Summary: Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]
  • Mouse(225467) protein geranylgeranyltransferase type I, beta subunit
  • Rat(81746) protein geranylgeranyltransferase type I, beta subunit
  • Zebrafish(570808) protein geranylgeranyltransferase type I, beta subunit
  • chicken(770633) protein geranylgeranyltransferase type I, beta subunit
  • domestic cat(101089829) protein geranylgeranyltransferase type I, beta subunit
  • dog(481440) protein geranylgeranyltransferase type I, beta subunit
  • cow(509322) protein geranylgeranyltransferase type I, beta subunit
  • sheep(101123045) protein geranylgeranyltransferase type I, beta subunit
  • domestic guinea pig(100735292) protein geranylgeranyltransferase type I, beta subunit
  • naked mole-rat(101723510) protein geranylgeranyltransferase type I, beta subunit

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Antibodies

Référence du produit
Description
Espèces réactives
Application
WH0005229M2
Monoclonal Anti-PGGT1B antibody produced in mouse, clone 5E4, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
G5169
GGTI 298 trifluoroacetate salt hydrate, ≥90% (HPLC), film,
Espèce(s)
human
259926
Itaconic anhydride, 95%,
Espèce(s)
human
G5294
GGTI-2133, ≥98% (HPLC), solid,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EHNC027361
MISSION® esiRNA, targeting human PGGT1B (1),
Espèce(s)
human
EMU041131
MISSION® esiRNA, targeting mouse Pggt1b,
Espèce(s)
mouse
EHU112171
MISSION® esiRNA, targeting human PGGT1B (2),
Espèce(s)
human