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Merck

P2RY1

purinergic receptor P2Y, G-protein coupled, 1

Synonymes:
P2Y1
Espèce(s):
Human P2RY1 (5028), Mouse P2ry1 (18441), Rat P2ry1 (25265), chicken P2RY1 (396275), dog P2RY1 (449621), domestic cat P2RY1 (101090795), cow P2RY1 (281963), sheep P2RY1 (101114407), Domestic Rabbit P2RY1 (100353792), domestic guinea pig P2ry1 (100135592)
ID UniProtKB:
P47900
ID du gène:
  • Human(5028) Summary: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]
  • Mouse(18441) purinergic receptor P2Y, G-protein coupled 1
  • Rat(25265) purinergic receptor P2Y, G-protein coupled, 1
  • chicken(396275) purinergic receptor P2Y, G-protein coupled, 1
  • dog(449621) purinergic receptor P2Y, G-protein coupled, 1
  • domestic cat(101090795) purinergic receptor P2Y, G-protein coupled, 1
  • cow(281963) purinergic receptor P2Y, G-protein coupled, 1
  • sheep(101114407) purinergic receptor P2Y, G-protein coupled, 1
  • Domestic Rabbit(100353792) purinergic receptor P2Y, G-protein coupled, 1
  • domestic guinea pig(100135592) purinergic receptor P2Y, G-protein coupled 1

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
01905
Adenosine 5′-diphosphate, ≥95% (HPLC),
Espèce(s)
human
U4125
Uridine 5′-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae, 95-100%,
Espèce(s)
human

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
M3808
MRS 2179 ammonium salt hydrate, ≥98% (HPLC),
Espèce(s)
human
A2754
Adénosine 5′-diphosphate sodium salt, bacterial, ≥95% (HPLC),
Espèce(s)
human
A5285
Adenosine 5′-diphosphate monopotassium salt dihydrate, bacterial, ≥95%, powder,
Espèce(s)
human
01905
Adenosine 5′-diphosphate, ≥95% (HPLC),
Espèce(s)
human
N8652
NF 023 hydrate, ≥98% (HPLC), solid,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA015577
Anti-P2RY1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
SAB1402298
Monoclonal Anti-P2RY1, (N-terminal) antibody produced in mouse, clone 4C2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
western blot
SAB2109077
Anti-P2RY1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
SAB1406210
Anti-P2RY1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
AB9263
Anti-P2Y1 Antibody, Chemicon®, from rabbit,
Espèces réactives
human
Application
immunohistochemistry

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
S2671
Suramin sodium salt, ≥98% (TLC),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EMU017741
MISSION® esiRNA, targeting mouse P2ry1,
Espèce(s)
mouse
EHU033811
MISSION® esiRNA, targeting human P2RY1,
Espèce(s)
human