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Merck

NRGN

neurogranin (protein kinase C substrate, RC3)

Synonymes:
RC3, hng
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4900) Summary: Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008]
  • Mouse(64011) neurogranin
  • Rat(64356) neurogranin
  • domestic guinea pig(100722735) neurogranin (protein kinase C substrate, RC3)
  • naked mole-rat(101719402) neurogranin (protein kinase C substrate, RC3)
  • sheep(101107911) neurogranin (protein kinase C substrate, RC3)
  • chicken(768940) neurogranin (protein kinase C substrate, RC3)
  • cow(616955) neurogranin (protein kinase C substrate, RC3)
  • domestic cat(101080823) neurogranin (protein kinase C substrate, RC3)
  • dog(479401) neurogranin (protein kinase C substrate, RC3)

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anticorps anti-neurogranine, Chemicon®, from rabbit,
Espèces réactives
bovine, chicken, human, mouse, rat, zebrafish
Application
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-NRGN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-Neurogranin, from rabbit, purified by affinity chromatography,
Espèces réactives
bovine, goat, human, mouse, rat
Application
immunohistochemistry
western blot
Anti-NRGN antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
Anti-phospho-Neurogranin (Ser36)/Neuromodulin (Ser41) Antibody, serum, from rabbit,
Espèces réactives
mouse, rat
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human NRGN,
Espèce(s)
human