NOX4
NADPH oxidase 4
KOX, KOX-1, RENOX
Human NOX4 (50507), Mouse Nox4 (50490), Rat Nox4 (85431), chicken NOX4 (419012), dog NOX4 (485144), Horse NOX4 (100050321), cow NOX4 (378474), sheep NOX4 (100034665), Domestic Rabbit NOX4 (100339697), naked mole-rat Nox4 (101726508)
- Human(50507) Summary: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
- Mouse(50490) NADPH oxidase 4
- Rat(85431) NADPH oxidase 4
- chicken(419012) NADPH oxidase 4
- dog(485144) NADPH oxidase 4
- Horse(100050321) NADPH oxidase 4
- cow(378474) NADPH oxidase 4
- sheep(100034665) NADPH oxidase 4
- Domestic Rabbit(100339697) NADPH oxidase 4
- naked mole-rat(101726508) NADPH oxidase 4
- domestic guinea pig(100727664) NADPH oxidase 4
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Antibodies
Anti-NOX4 Antibody, clone 10A8.1, culture supernatant, clone 10A8.1, from mouse,
human
immunohistochemistry
western blot
western blot
Anti- NOX4 antibody produced in rabbit, ,
human, mouse, rat
immunohistochemistry
western blot
western blot
ANTI-NOX4 (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
human
western blot