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Merck

NEFL

neurofilament, light polypeptide

Synonymes:
CMT1F, CMT2E, NF-L, NF68, NFL
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4747) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
  • Mouse(18039) neurofilament, light polypeptide
  • Rat(83613) neurofilament, light polypeptide
  • chicken(419528) neurofilament, light polypeptide
  • cow(281348) neurofilament, light polypeptide
  • domestic cat(101081039) neurofilament, light polypeptide
  • dog(477378) neurofilament, light polypeptide
  • naked mole-rat(101704332) neurofilament, light polypeptide
  • domestic guinea pig(100731797) neurofilament, light polypeptide
  • sheep(101119539) neurofilament, light polypeptide

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anticorps anti-chaîne légère du neurofilament, serum, Chemicon®,
Espèces réactives
bovine, canine, feline, human, mouse, pig, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Neurofilament 68 antibody produced in mouse, clone NR4, ascites fluid,
Espèces réactives
chicken, human, pig, rat
Application
immunohistochemistry
microarray

western blot
Anti-Neurofilament L Antibody, clone 1E13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anticorps anti-neurofilament 70 kDa, clone DA2, culture supernatant, clone DA2, Chemicon®,
Espèces réactives
bovine, human, mouse, pig, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-phospho-NFL (Ser473) Antibody, clone 4F8, clone 4F8, from mouse,
Espèces réactives
bovine, human, mouse, porcine, rat, rhesus macaque
Application
immunohistochemistry
western blot

Proteins

Référence du produit
Description
Espèce(s)
Neurofilament 70 kDa, porcine, ,
Espèce(s)

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human NEFL,
Espèce(s)
human